Frédéric Jules Sichel (14 May 1802 – 11 November 1868) was a German-born, French physician and entomologist.

Sichel was born in Frankfurt am Main. From 1820 he studied medicine at the universities of Würzburg, Tübingen and Berlin, then from 1825 to 1829 worked as assistant to ophthalmologist Friedrich Jäger von Jaxtthal in Vienna. In 1829 he relocated to Paris, where in 1833 he received his doctorate with the dissertation-thesis "Propositions générales sur l'ophthalmologie, suivies de l'histoire de l'ophthalmie rhumatismale". In 1833 he acquired French citizenship.

In 1832 he established the first ophthalmic clinic in Paris, and for a period of time, gave courses in ophthalmology at the Hôpital Saint-Antoine. He is credited with bringing modern ophthalmology to France from Austria and Germany. Sichel trained several famous ophthalmologists (Louis-Auguste Desmarres, Charles Deval, Charles de Hübsch and Wiktor Szokalski) at his Paris clinic. He was interested in oriental languages and archaeology, writing extensively on the seals of Roman doctors. In entomology he specialized in Hymenoptera – his collection being donated to the Muséum National d'Histoire Naturelle. Sichel died in Paris.